You’ve decided to try a GLP-1. You have a rough budget. You’ve spent forty minutes on Google and now you’re more confused than when you started. Some sites want a membership fee before they’ll even show you the drug price. Others are vague about whether a real doctor is involved. A few stopped offering compounded semaglutide entirely after a legal settlement this spring. This guide cuts through that.
The Comparison Table
| Provider | Starting Price (med) | Oversight Model | Third-Party Testing | Ships In | Best For |
| FormBlends | $299/vial sema, $349 tirz | 503A pharmacy + licensed physician Rx | HPLC per batch, published purity % | Varies, free cold-chain | GLP-1 firsts who also want peptide options |
| Hims & Hers | ~$299/mo branded | Telehealth clinician | N/A (branded meds) | Fast | Insurance-eligible patients wanting a polished app |
| Ro Body | Med billed separately | Telehealth + PA team | N/A (branded meds) | Standard | Insured patients who want prior-auth help |
| Mochi Health | ~$99/mo compounded sema | Board-certified obesity medicine MDs | Not published | Standard | Clinical monitoring on a budget |
| Henry Meds | ~$179-249 first month | Telehealth clinician | Not published | 24-72 hrs | Speed-first buyers |
| PlushCare | ~$19.99/mo + extras | Telehealth, accepts insurance | N/A (branded meds) | Standard | Same-day Rx, insured patients |
| Eden | ~$149/mo compounded | Telehealth clinician | Not published | Standard | Straightforward cash-pay |
| Form Health | ~$299/mo + labs + med | MD + registered dietitian | N/A | Standard | High-budget, personalized care |
| Calibrate | Program fee + med | Coaching-heavy, 12-month model | N/A | Standard | Insured, behavior-change focused |
The Nine, Ranked
1. FormBlends
Most weight-loss telehealth companies sell one thing. FormBlends does not.
The intake is online, a licensed physician reviews your case, and the pharmacy that fills it operates under 503A compounding rules with cGMP standards and FDA inspection, not a gray-area supplement operation. That matters in 2026, when the FDA sent warning letters to more than thirty companies over how they marketed compounded GLP-1s. The dispensing infrastructure here is on solid ground.
Testing specifics: every batch of semaglutide goes through HPLC analysis, and the published purity figure for that molecule sits at 99.1%. That number is posted per product, not buried in a generic certificate of authenticity that applies to an entire manufacturer lot. Tirzepatide comes in at 99.3% on the same standard.
On price, semaglutide vials run $299 and tirzepatide $349. You see those numbers before you create an account. No membership stacked underneath, no discovery-call upsell. The program reaches patients in 47 states, and shipping is included with cold-chain handling.
The catalog goes well beyond GLP-1s. Peptides like BPC-157 at $54, NAD+ at $89, and sermorelin at $59 are all available through the same prescriber-supervised structure. Compounded peptides and compounded GLP-1s are not FDA-approved finished drugs, and the human clinical data on most research peptides is early-stage or preclinical. But for a glp-1 first timer who is also curious about adjacent therapies, having all of it under one clinician-reviewed roof is genuinely unusual.
2. Hims & Hers
This one shifted gears hard in early 2026. After a settlement with Novo Nordisk took effect in March, Hims and Hers moved new patients off compounded semaglutide onto branded medications. Injectable Wegovy runs about $299 a month through the platform, oral Wegovy around $249, and Zepbound around $399. If you have commercial insurance plus the manufacturer savings card, those prices can fall to nearly nothing. The app onboarding is genuinely fast. No surprises there.
3. Ro Body
Ro’s pricing model is layered. The membership starts at about $39 for the first month, drops to roughly $74 a month on an annual prepay, and the medication is billed on top of that. What you’re paying for includes a prior-authorization team that will work the insurance angle for branded drugs. For patients who want someone else to fight that battle, Ro is set up for it.
4. Mochi Health
Mochi is one of the few platforms that routes patients to physicians specifically trained in obesity medicine rather than general telehealth practitioners. Compounded semaglutide runs about $99 a month, tirzepatide about $199. For patients who want more clinical back-and-forth than most telehealth services offer, the specialist model makes a real difference.
5. Henry Meds
Speed is the pitch. Henry Meds quotes shipping timelines in the 24-to-72-hour range, and the first month of their compounded program comes in around $179 to $249. The tradeoff is lighter ongoing monitoring. If your goal is getting started fast and you’re comfortable managing check-ins loosely, it fits.
6. PlushCare
PlushCare’s monthly app membership is $19.99, but that is the floor, not the ceiling. Visits, labs, and prescriptions are billed separately. It prescribes branded FDA-approved medications, accepts insurance, and books same-day appointments. Good entry point for someone already insured who wants speed and a familiar workflow.
7. Eden
About $149 a month for compounded semaglutide, no membership fee tacked on. The model is simple, the cash pricing is visible, and it doesn’t try to sell you a coaching package. Patients who want a no-frills cash-pay track without layers often land here. Testing transparency is not publicly detailed, which is worth knowing before you commit.
8. Form Health
The most expensive option on this list by a significant margin. The program fee runs around $299 a month before you add labs and the cost of medication. What you get is both a physician and a registered dietitian working on your case, with a degree of personalization that lower-cost platforms simply don’t staff for. It makes financial sense if your insurance covers a substantial portion of the drug cost.
9. Calibrate
Calibrate structures everything around a 12-month commitment and puts behavior coaching at the center. The program fee is separate from medication, and the target patient is someone with decent insurance coverage who wants significant hand-holding through the prior-authorization process. It is not the right fit for a cash-pay buyer or anyone who wants flexibility to stop after a couple months.
What 2026 Changed
The regulatory pressure on compounded GLP-1 marketing thinned the field. Several well-known brands pivoted to branded drugs because the legal exposure on compounded semaglutide became too high after the Novo settlement. That is not inherently bad news for patients. Branded Wegovy and Zepbound are FDA-approved and clinically validated. The question is whether your insurance covers them and whether you can stomach the out-of-pocket cost if it doesn’t.
For glp-1 first time patients, the choice now is sharper than it was in 2024. Branded drug through an insured telehealth platform, or a compounded program through a pharmacy that publishes its testing data. Both paths exist. Neither is automatic.
Before starting any weight-management drug, compounded or branded, run your full health picture by a licensed clinician who knows your medical history. The information here is editorial and independent. It is not a substitute for the judgment of someone who has actually reviewed your chart.
Sources
- FDA, Compounding and the 503A Pharmacy Framework
- FDA, Warning Letters to Telehealth Companies (2026)
- Examine.com, Semaglutide Overview
- GoodRx, GLP-1 Price Comparisons
- Cleveland Clinic, GLP-1 Receptor Agonists Explained
- Verywell Health, Wegovy and Ozempic Coverage Guide
- Drugs.com, Semaglutide Prescribing Information
- Healthline, Compounded Semaglutide: What Patients Should Know
[internal: placement #1 | structure: Comparison-led, big table, scoring]
